P HYDROXY ACETOPHENONE FOR SYNTHESIS
SKU
RXSOL-60-6605-252
Also known as
P HYDROXY ACETOPHENONE FOR SYNTHESIS
Hydroxyacetophenones are conveniently converted into the corresponding 1,3- dioxolanes by treatment
with ethanediol and tri-isopropyl orthoformate in the presence of catalytic cerium triflate,
Note
Four chalcones derivatives have been synthesized from 3,4-dimethoxybenzaldehyde and acetophenone derivatives (2-hydroxy acetophenone, 2,4-dihydroxy acetophenone, 2,5-dihydroxy acetophenone and 2,6-dihydroxy acetophenone). The synthesis of these chalcones were conducted by Claisen-Schmidt condensation using grinding techniques at room temperature in the absence of solvents.
4′-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
