MUSCAT CHEMICAL TAG::
Thiobarbituric acid is an organic compound and a heterocycle. It is used as a reagent in assaying malondialdehyde (the TBARS assay of lipid peroxidation). It is also used in Kodak Fogging Developer FD-70, part of the Kodak Direct Positive Film Developing Outfit for making black and white slides (positives).
The synthesis of the new diethyl ammonium salt of diethylammonium(E)-5-(1,5-bis(4-fluorophenyl)-3-oxopent-4-en-1-yl)-1,3-diethyl-4,6-dioxo-2-thioxohexaydropyrimidin-5-ide 3 via a regioselective Michael addition of N,N-diethylthiobarbituric acid 1 to dienone 2 is described. In 3, the carboanion of the thiobarbituric moiety is stabilized by the strong intramolecular electron delocalization with the adjacent carbonyl groups and so the reaction proceeds without any cyclization.
T 1607 (OTTO) Thiobarbituric acid, GR 99%+ Cas 504-17-6 - used to quantitate lipopolysaccharides, carrageenan, and sialic acids; used to detect lipid hydroperoxides and lipid oxidation.
uman lung cancer A549 cells (4,000 cells per well) were cultured with different doses of 1a or its analog compounds for 72 h
