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Mono Propylene Glycol USP/IND

Propylene glycol is a humectant, which means that it is an ingredient that is added to cosmetics to increase Moisture Retention in skin and hair. Propylene glycol is well tolerated by the skin and shouldn't cause redness or irritation.

Remarks

Propylene Glycol USP,  is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications.It is a light, transparent liquid, almost odorless and with low volatility. It is completely soluble in water and in most organic solvents. In addition, all propylene glycols have a great capacity to hold and dissolve active ingredients equally which allows them to serve as carriers of aromas, flavors, dyes and moisture. 

Propylene Glycol USP is tested for compliance with the current USP, EP, and Japanese Pharmacopoeia (JP) specifications plus the Food Chemical Codex (FCC); it also complies with the Brazilian Pharmacopoeia, and other pharmaceutical, cosmetic and food regulations in the global markets where it is sold. It is listed by the Cosmetic, Toiletry and Fragrance Association as an approved ingredient in cosmetics and its use is reviewed by the Cosmetic Ingredient Review (CIR). Propylene Glycol USP is Kosher certified and complies with Halal requirements.

Tag Identification

Propylene glycol, also called 1,2-propanediol or propane-1,2-diol, is an organic compound with formula C3H8O2
Melting point: -59 °C
Density: 1.04 g/cm³
Boiling point: 186.2 °C
Formula: C3H8O2
Molar mass: 76.09 g/mol
IUPAC ID: propane-1,2-diol

Note

Propylene glycol is tolerated well by the skin and shouldn't cause redness or irritation. Propylene glycol is a penetration-enhancing humectant.
 

Propylene Glycol USP is a widely used ingredient in pharmaceutical, food, cosmetic, personal care, flavors and animal feed applications; an overview of typical uses of Propylene Glycol USP as below.It must be emphasized that it is the user’s responsibility to consult area and country-specific regulations for details of approved use.

  1. Pharmaceuticals - Solvent for active ingredients in oral, and topical products.
     
  2. Cosmetics & Personal Care - Solvent, coupling agent, carrier, emulsion stabilizer, softening agent, viscosity modifier and humectant in many types of cosmetics and personal care products such as skincare, sun care, shampoo, bath/shower products, toothpastes, mouthwashes, shaving products and baby care products.
     
  3. Flavors & Fragrances - Solvent and extraction solvent of flavors and fragrances for applications in food, beverages, perfumes and cosmetics.
     
  4. Food - Various applications as a direct food additive (E 1520) such as a carrier or carrier solvent for colors, emulsifiers, antioxidants and enzymes (in Europe with maximum 1 g/kg in human foodstuffs), and humectant and stabilizer in fruits, vegetables and bakery goods (except in Europe). Propylene Glycol USP is also applied in indirect contact food applications, such as a low temperature heat-transfer fluid in the brewing, dairy and ice cream industries and for food storage facilities, an equipment cleaner fluid or a solvent for printing inks.
     
  5. Pet foods & Animal Feed - Humectant, emulsifier, preservative, solvent foradditives, energy source and aid for prevention of ketosis (acetonemia) in dairycattle. In EMEA a specific tailor made Propylene Glycol Animal Feed is offered forthis application.

Description: Propylene Glycol USP

Test Description

Specification Limits

Min. Max.

Unit  of Measure

Test  Method

Propylene Glycol, on a Dry basis

99.5

%(w/w)

HOC 0540

Acidity as acetic acid

0.002

%(w/w)

HOC 0210

Chlorides

0.5

ppm

HOC 0221

Colour, Pt-Co

10

APHA Colour

HOC 0641

Heavy Metals as Pb

5

ppm

HOC 0274

Iron

0.5

ppm

HOC 0290

Water

0.2

%(w/w)

HOC 0316

Arsenic as As

1

HOC 0242

Distillation @ 760 mm Hg

Initial Boiling Point

186

oC

HOC 0154

Drying Point

189

oC

HOC 0154

Residue on Ignition

0

0.005

%(w/w)

HOC 0140

Specific Gravity@20/20 oC

1.0377

1.0389

HOC 0132

Specific Gravity@25/25 oC

1.0352

1.0364

HOC 0132

Sulphate

0

0.006

%(w/w)

HOC 0225

It is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products. It is a solvent for food colors and flavors, and in the paint and plastics industries. Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions.

According to the Material Safety Data Sheet on propylene glycol, the chemical is a strong skin irritant, and has been implicated in contact dermatitis. 


Storage and Handling :

Propylene Glycol USP is stable for at least two years when stored at ambient temperatures in closed containers and away from sunlight and other sources of UV light.Where product heating is utilized (i.e. for bulk storage and/or transport containers) the product temperature should be controlled to prevent unintentional overheating over extended periods as this may potentially lead to accelerated oxidative degradation of the product.

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