Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer,…
Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical
industry as a solvent, plasticizer, surfactant, ointment and suppository base, and tablet and capsule lubricant.
Polyethylene glycol (PEG) is an inert amphiphilic polymer in contrast to ethylene glycol oxide, which is commonly known as a toxic compound used for synthesis of PEG. A consequence of its low reactivity is that PEG does not exhibit toxicity in humans also because mammals do not have enzymes which are able to metabolize PEG. Therefore, once ingested or parenterally administered PEG remains intact until it is eliminated via urine or feces.
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