HATU FOR SYNTHESIS
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During the synthesis of peptide nucleic acid (PNA) analogues, HATU was successfully used as a coupling reagent along with collidine, both in solution and solid phase. Furthermore, the synthetic route towards dehydrodidemnin B was improved by the use of HATU.
Key facts
- Product
- HATU FOR SYNTHESIS
- Part No.
- RXSOL-60-6604-663
- Category
- Lab Chemical
- Supplier
- Muscat Chemical, Barka, South Al Batinah, Oman
- Delivery
- Muscat, Sohar, Salalah, Duqm, Nizwa, Sur, Barka and Gulf ports
- Documents
- MSDS and TDS on request
- Pricing
- Quote on request — contact us or WhatsApp +968 77333599
HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used inpeptide couplingchemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base(N,N-diisopropylethylamine, DIPEA) to form amide bonds.
Dosage
A mide bonds are one of the underpinning linkages in all living systems and are fundamental within drug discovery.