Chromotropic acid disodium salt dihydrate may be employed as a chromogenic reagent for the quantification of dipyrone in various pharmaceutical preparations.
The formation of the azo-dye using chromotropic acid as a coupling agent was applied to
the determination of five sulphonamides. The spectrophotometric studies as well as microanalysis
of the studied sulphonamides- chromotropic acid azo dyes revealed the existence of the 1:l
coupling product. The absorbance of the formed azo dye is measured at 510 nrn, and has a large
molar absorptivity .
accuracy and precision over the concentration range used.The formation of the azo-dye using chromotropic acid as a coupling agent was applied to
the determination of five sulphonamides. The spectrophotometric studies as well as microanalysis
of the studied sulphonamides- chromotropic acid azo dyes revealed the existence of the 1:l
coupling product. The absorbance of the formed azo dye is measured at 510 nrn, and has a large
molar absorptivity ( E = 2.87 - 3.29 x lo4 1 mol-'cm-I). Beer's law was obeyed over the
concentration range 0.5-9.0 pg rnl-'. The assay results of pharmaceutical formulations showed good
accuracy and precision over the concentration range used.
CHROMOTROPIC ACID DISODIUM SALT 98 Supplier Oman Muscat Barka Salalah Sohar Ruwi Mutrah Nizwa Al Hamra Manah
Email:- mail@muscatchemical.com
