Furfurylamine is an aromatic amine typically formed by the reductive amination of furfural with ammonia.
The pharmaceutical drug furtrethonium, a parasympathomimetic cholinergic, is a trimethyl ammonium
derivative of furfurylamine. Furfurylamine also has use in the synthesis of Barmastine.
A review of the various methods for the asymmetric syntheses of optically active α-furfuryl amine derivatives and their application to the asymmetric syntheses of natural products is described.
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