During the synthesis of peptide nucleic acid (PNA) analogues, HATU was successfully used as a coupling reagent along with collidine, both in solution and solid phase. Furthermore, the synthetic route towards dehydrodidemnin B was improved by the use of HATU.
Current methods towards their synthesis frequently rely on the use of dipolar aprotic solvents; however, due to increasingly stringent regulations and growing societal pressures, safe and more sustainable alternatives are highly sought after.
HATU FOR SYNTHESIS Supplier Oman Muscat Barka Salalah Sohar Ruwi Mutrah Nizwa Al Hamra Manah
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